Cost variation analysis of commonly prescribed oral antipsychotic drugs available in India-a pharmacoeconomic perspective

Background: Antipsychotics are commonly prescribed for a variety of psychiatric disorders which require prolonged treatment. If costly brand is prescribed, it reduces patient compliance, especially in the lower socio-economic groups. Awareness about cost variation among different brands will guide an economically effective prescription by treating physician.Methods: The used oral antipsychotic drugs available Indian market manufactured companies, same strength, number and dosage form was obtained from latest CIMS, MIMS, India drug Index. ratio percentage were calculated each. also noted Jan Aushadhi generic medicines portal comparison made. Results: above 100% with most like haloperidol (517%), trifluoperazine (504.12%), risperidone (485.27%), chlorpromazine (436.35%), aripiprazole (340.34%), flupenthixol (293.12%), olanzapine (245%), ziprasidone (176.02%), amisulpride (169.44%), quetiapine (163.16%). Percentage between branded ranged 400-1050%.Conclusions: There substantial various drugs. Stigma surrounding needs to be addressed. More need included under National list essential DPCO (Drug price control order) so that there can ceiling on maximum price.